MOTS-c 10MG

Product Overview

MOTS-c 10MG is a synthetic mitochondrial-derived peptide research material, supplied as white to off-white lyophilised powder in a 10mg catalogue presentation (SKU MS10). This page describes the stated research identity and batch-oriented catalogue specification; it does not provide an administration protocol.

MOTS-c is studied as a mitochondrial open-reading-frame-derived peptide involved in cellular stress and metabolic signalling. Published work includes cell, animal and early human observational or experimental research.

Identity and Specifications

• Product: MOTS-c 10MG
• SKU: MS10
• Format: White to off-white lyophilised powder
• Synonyms: MOTS-c, Mitochondrial Open Reading Frame of the 12S rRNA Type-c
• Catalogue purity specification: ≥99%
• CAS number: 1627580-64-6
• Molecular formula: C101H152N28O22S2
• Molecular weight: 2174.6 g/mol
• Amount: 10mg

Research Context

The following themes summarise published research on the named molecule or components. They are research contexts, not claims about the supplied ExtolX batch.

Areas of Research

• mitochondrial-to-nuclear signalling
• AMPK-associated pathway research
• cellular stress and metabolic homeostasis
• exercise and ageing-related biomarker models

Evidence Quality and Limitations

The evidence is mainly preclinical and mechanistic. It does not establish clinical benefit, safe administration or equivalence of this supplied material.

Storage and Handling

Before reconstitution: Keep the lyophilised vial sealed, dry and protected from light at −20°C or below, subject to the batch-specific supplier documentation. Published human MOTS-c reference data support frozen storage, but the identity, counter-ion and formulation of this ExtolX batch have not been independently matched to those references. Allow a cold vial to reach room temperature before opening to reduce condensation.

After reconstitution: Stability depends on the exact salt or formulation, solvent, concentration, pH and container. Prepare only what the validated method requires. If that method supports frozen storage, use single-use aliquots and avoid repeated freeze–thaw cycles. Use clean laboratory technique, avoid vigorous agitation, and record the preparation and storage history. No numerical solution shelf life has been verified for this ExtolX batch.

Compatibility Limitations

Do not infer solubility or stability from another peptide, blend, amount or pharmaceutical formulation. Use small-scale method development and appropriate analytical controls before committing valuable material.

Laboratory Safety

Handle only in an appropriately equipped laboratory by trained personnel. Use a task-specific risk assessment, suitable personal protective equipment and applicable safety documentation. Avoid ingestion, inhalation, skin contact and environmental release, and dispose of waste in accordance with local requirements.

Sources

• MedChemExpress storage references: human MOTS-c and human MOTS-c acetate
• PubMed: Original MOTS-c study
• PubMed: MOTS-c signalling review
• PubMed: MOTS-c research review
• FDA: Safety concerns for certain compounded peptide substances

Scientific sources last reviewed: 23 August 2026.

Research Use Agreement & Disclaimer

For laboratory research use only. Not for human or veterinary use. Purchasers are responsible for lawful handling, storage and disposal in accordance with applicable regulations and good laboratory practice. Product information is educational and is not medical advice or evidence of efficacy.